Archive for October, 2008

Journal of Family Practice - Antidepressant treatment reduces poststroke mortality

Tuesday, October 28th, 2008

Jorge RE, Robinson RG, Arndt S, Starkstein S. Mortality and poststroke depression: a placebo controlled trial of anti-depressants. Am J Psychiatry 2003; 160:1823-1829.
* PRACTICE RECOMMENDATIONS
Treatment with either fluoxetine or nortriptyline for 12 weeks during the fir…

HealthDay - Improving the Odds for Stroke Survivors

Wednesday, October 22nd, 2008

Giving antidepressants to stroke survivors — whether they’re depressed or not — may improve their chances of living longer.
That startling finding comes from a University of Iowa study in the October issue of the American Journal of Psychiatry .
The study included 104 stroke patients randomly assigned to receive nortriptyline (Aventyl or Pamelor), fluoxetine (Prozac) or a placebo for three months after their str…

Business Wire - CombinatoRx Announces Initiation of Phase 2a Clinical Study of CRx-191 in Psoriasis

Saturday, October 18th, 2008

— First Patient Dosed –
CAMBRIDGE, Mass. — CombinatoRx, Incorporated (NASDAQ: CRXX) today announced that it has begun dosing of patients in a Phase 2a clinical trial in psoriasis with CRx-191, a top…

American Family Physician - Bupropion and Nortriptyline for smoking cessation

Tuesday, October 14th, 2008

The most effective technique for reducing the risk of developing chronic obstructive pulmonary disease (COPD) is smoking cessation. Patients with COPD who successfully stop smoking have been shown to have an improvem…

American Family Physician - Drug therapy and psychologic support in smoking cessation - Tips from Other Journals

Saturday, October 11th, 2008

Bupropion and nortriptyline are effective adjuncts in the treatment of tobacco dependency. Both have been proved to improve abstinence rates compared to placebo. However, in the trials that studied the effectiveness of these agents, part…

American Family Physician - Nortriptyline used as a smoking cessation adjuvant - Tips from Other Journals - Brief Article

Monday, October 6th, 2008

One of the most preventable causes of morbidity and mortality in the United States is cigarette smoking. It was estimated that smoking-related disease would lead to more than 400,000 deaths in the United States in 2001. Smoking cessation before 50 years of age has been shown to reduce all causes of death by 50 percent in the following 16 years. Smoking cessation can increase life expectancy even in persons who sto…