Archive for November 3rd, 2008

Clinical Psychiatry News - Low remission seen with third antidepressant: STAR*D trial calls into question the practice of switching classes when an SSRI doesn’t help.(selective serotonin…

Monday, November 3rd, 2008

Less than 20% of patients switched to a third consecutive antidepressant for major depressive disorder achieved remission in a study published by the STAR*D trial investigators.

They reported low remission rates for mirtazapine and nortriptyline, the two medications compared in the third phase of the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial (Am. …