Teva Pharmaceutical Industries (NASDAQ-TEVIY) of Jerusalem announced that the U.S. Food and Drug Administration approved Teva’s sixth drug application in 1995. The application permits Teva to manufacture and market Nortriptyline Hydrochloride capsules. Nortriptyline is a generic equivalent of S…
Two recent reports involved incorrect dosing of the tricyclic antidepressant nortriptyline (marketed as Pamelor, Aventyl, and, in Australia, Nortab and Allegron) when ordered for neuropathic pain syndromes. The cases involved 10 m…
CAMBRIDGE, Mass. — CombinatoRx, Incorporated (NASDAQ: CRXX) today announced positive results of its single blind, phase 2, proof-of-concept clinical trial of CRx-170 in patients with asthma. CRx-170 is a novel synergistic combination drug candidate containing low dose budesonide and low dose nortriptyline. In this trial CRx-170 provided clinical benefit on FEV1 and demonstrated activity on i…
