Clinical Psychiatry News - Varenicline, antidepressants help smokers quit.(Addiction Psychiatry)(Clinical report)
Varenicline triples the likelihood that a smoker will quit, compared with placebo, and bupropion and nortriptyline double the odds, according to a pair of evidence reviews published Jan. 24.
The Cochrane Collaboration review of varenicline, a nicotine receptor agonist, based its findings on five randomized controlled trials that included more than 4,900 people, more than 2,400 of whom took varenicline (Cochrane Database Syst. Rev. 2007 Jan. 24 [Epub doi: 10.1002/14651858.CD006103.pub2]).
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Findings were validated in all of the studies included in the meta-analysis by measuring …
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